TPEQM-DMA
TPEQM-DMA is a NIR-II photosensitizer. TPEQM-DMA accumulates in cancerous mitochondria, and inhibits cancer cell growth. TPEQM-DMA has potent type-I phototherapeutic efficacy to overcome the intrinsic pitfalls of PDT in combating hypoxic tumors[1].
Product Specifications
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tpeqm-dma.html
Solubility
10 mM in DMSO
Smiles
CN(C)C1=CC=C(/C(C2=CC=C(N(C)C)C=C2)=C(C3=CC=C(/C=C/C4=CC=[N+](C)C5=C4C=CC=C5)C=C3)\C6=CC=CC=C6)C=C1.F[P-](F)(F)(F)(F)F
Molecular Formula
C42H40F6N3P
Molecular Weight
731.75
References & Citations
[1]Zhuang J, et al. Efficient NIR-II Type-I AIE Photosensitizer for Mitochondria-Targeted Photodynamic Therapy through Synergistic Apoptosis-Ferroptosis. ACS Nano. 2023 May 23;17 (10) :9110-9125.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
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