Gamma-Glutamyl Transferase-IN-2
Gamma-Glutamyl Transferase-IN-2 (compound 4dq) is a β-carboline 1-hydrazide inhibitor with antifungal and antibacterial activities, targeting to glutamyltransferase. Gamma-Glutamyl Transferase-IN-2 acts function by resulting the accumulation of reactive oxygen species, destruction of cell membranes, and dysregulation of histone acetylation[1].
Product Specifications
CAS Number
2956809-82-6
UNSPSC
12352005
Target
Fungal; γ-Glutamyl Transferase (GGT)
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gamma-glutamyl-transferase-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC(C(N)=O)=CC2=C1NC3=CC=CC=C32)NNC4=C(C=C(C=C4)F)F
Molecular Formula
C19H13F2N5O2
Molecular Weight
381.34
References & Citations
[1]Sheng T, et al. Chromatography-Free Synthesis of β-Carboline 1-Hydrazides and an Investigation of the Mechanism of Their Bioactivity: The Discovery of -Carbolines as Promising Antifungal and Antibacterial Candidates. J Med Chem. 2023 Jul 13;66 (13) :9040-9056.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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