RdRP-IN-6

RdRP-IN-6 (compound 27) inhibits RNA dependent-RNA polymerase (RdRp) with an IC90 value of 14.1 μM. RdRP-IN-6 can be used for research on antiviral and anticancer[1].

Product Specifications

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/rdrp-in-6.html

Solubility

10 mM in DMSO

Smiles

O=[P@@](N[C@H](C(OCC(CC)CC)=O)C)(OC[C@@H]1[C@@H](O[Si](C(C)(C)C)(C)C)[C@H](O[Si](C(C)(C)C)(C)C)[C@](C2=CNN=N2)(C3=CC=C4C(N)=NC=NN34)C1)OC5=CC=CC=C5

Molecular Formula

C41H67N8O7PSi2

Molecular Weight

871.16

References & Citations

[1]Cardoza S, et al. Multistep Synthesis of Analogues of Remdesivir: Incorporating Heterocycles at the C-1' Position. J Org Chem. 2023 Jul 7;88 (13) :9105-9122.