Anti-hepatic fibrosis agent 2
Anti-hepatic fibrosis agent 2 (Compound 6k) is an orally active COL1A1 inhibitor. Anti-hepatic fibrosis agent 2 is an anti-fibrogenic agent targeting ewing sarcoma breakpoint region 1 (EWSR1) [1].
Product Specifications
CAS Number
[2380421-60-1]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-hepatic-fibrosis-agent-2.html
Solubility
10 mM in DMSO
Smiles
[H][C@]12[C@]3([H])CCCN1CCC[C@]2(CN(C(NC4=C(C=CC=C4CC)CC)=O)[C@@H]3CCCC)[H]
Molecular Formula
C26H41N3O
Molecular Weight
411.62
References & Citations
[1]Bao Y, et al. Evolution and Discovery of Matrine Derivatives as a New Class of Anti-Hepatic Fibrosis Agents Targeting Ewing Sarcoma Breakpoint Region 1 (EWSR1) . J Med Chem. 2023 Jun 22;66 (12) :7969-7987.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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