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Anti-hepatic fibrosis agent 2

Anti-hepatic fibrosis agent 2 (Compound 6k) is an orally active COL1A1 inhibitor. Anti-hepatic fibrosis agent 2 is an anti-fibrogenic agent targeting ewing sarcoma breakpoint region 1 (EWSR1) [1].

Product Specifications

CAS Number

[2380421-60-1]

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-hepatic-fibrosis-agent-2.html

Solubility

10 mM in DMSO

Smiles

[H][C@]12[C@]3([H])CCCN1CCC[C@]2(CN(C(NC4=C(C=CC=C4CC)CC)=O)[C@@H]3CCCC)[H]

Molecular Formula

C26H41N3O

Molecular Weight

411.62

References & Citations

[1]Bao Y, et al. Evolution and Discovery of Matrine Derivatives as a New Class of Anti-Hepatic Fibrosis Agents Targeting Ewing Sarcoma Breakpoint Region 1 (EWSR1) . J Med Chem. 2023 Jun 22;66 (12) :7969-7987.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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