α-Amylase/α-Glucosidase-IN-3

α-Amylase/α-Glucosidase-IN-3 (Compound 17) is an α-Amylase/α-Glucosidase dual inhibitor, with IC50s of 0.70 μM and 1.10 μM. α-Amylase/α-Glucosidase-IN-3 can be used for research of type-II diabetes mellitus[1].

Product Specifications

UNSPSC

12352005

Target

Amylases; Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-amylase-α-glucosidase-in-3.html

Solubility

10 mM in DMSO

Smiles

O=[N+](C1=CC=C(C2=NN=C(SC/C(C3=CC(Cl)=C(Cl)C=C3)=N/N=C/C4=CC(Cl)=C(Cl)C=C4)N2)C=C1)[O-]

Molecular Formula

C23H14Cl4N6O2S

Molecular Weight

580.27

References & Citations

[1]Khan I, et al. Synthesis and In Vitro α-Amylase and α-Glucosidase Dual Inhibitory Activities of 1,2,4-Triazole-Bearing bis-Hydrazone Derivatives and Their Molecular Docking Study. ACS Omega. 2023 Jun 5;8 (25) :22508-22522.