α-Amylase/α-Glucosidase-IN-3
α-Amylase/α-Glucosidase-IN-3 (Compound 17) is an α-Amylase/α-Glucosidase dual inhibitor, with IC50s of 0.70 μM and 1.10 μM. α-Amylase/α-Glucosidase-IN-3 can be used for research of type-II diabetes mellitus[1].
Product Specifications
UNSPSC
12352005
Target
Amylases; Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-amylase-α-glucosidase-in-3.html
Solubility
10 mM in DMSO
Smiles
O=[N+](C1=CC=C(C2=NN=C(SC/C(C3=CC(Cl)=C(Cl)C=C3)=N/N=C/C4=CC(Cl)=C(Cl)C=C4)N2)C=C1)[O-]
Molecular Formula
C23H14Cl4N6O2S
Molecular Weight
580.27
References & Citations
[1]Khan I, et al. Synthesis and In Vitro α-Amylase and α-Glucosidase Dual Inhibitory Activities of 1,2,4-Triazole-Bearing bis-Hydrazone Derivatives and Their Molecular Docking Study. ACS Omega. 2023 Jun 5;8 (25) :22508-22522.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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