Mcl-1 inhibitor 15

Mcl-1 inhibitor 15 (Compound (Ra) -15) is a Mcl-1 inhibitor (Ki: 0.02 nM) . Mcl-1 inhibitor 15 can be used for research of cancer[1].

Product Specifications

UNSPSC

12352005

Target

Bcl-2 Family

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mcl-1-inhibitor-15.html

Solubility

10 mM in DMSO

Smiles

CN1N=CC(CSCC2=NN(C)C(CCC3=CC(C=C(C=C4)F)=C4C(OCCCC5=C6C(O)=O)=C3)=C2)=C1C(C(Cl)=CC=C57)=C7N6CCN8CCOCC8

Molecular Formula

C40H42ClFN6O4S

Molecular Weight

757.32

References & Citations

[1]Demin S, et al. Macrocyclic Carbon-Linked Pyrazoles As Novel Inhibitors of MCL-1. ACS Med Chem Lett. 2023 Jul 3;14 (7) :955-961.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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