Mcl-1 inhibitor 14
Mcl-1 inhibitor 14 (Compound (Ra) -10) is an inhibitor of myeloid cell leukemia-1 (MCL-1) with an Ki of 0.018 nM and can be used for anticancer research[1].
Product Specifications
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mcl-1-inhibitor-14.html
Solubility
10 mM in DMSO
Smiles
CN1N=C(C(CSCC2=NN(C)C(CCC3=CC(C=C(C=C4)F)=C4C(OCCCC5=C6C(O)=O)=C3)=C2)=C1C(C(Cl)=CC=C57)=C7N6C)COCCOC
Molecular Formula
C39H41ClFN5O5S
Molecular Weight
746.29
References & Citations
[1]Demin S, et.al. Macrocyclic Carbon-Linked Pyrazoles As Novel Inhibitors of MCL-1. ACS Med Chem Lett. 2023 Jul 3;14 (7) :955-961.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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