Thio-NADP
Thio-NADP (S-NADP) is a nicotinic acid adenine dinucleotide phosphate (NAADP) inhibitor. Thio-NADP activates partial Ca2+ release[1].
Product Specifications
CAS Number
19254-05-8
Product Name Alternative
S-NADP
UNSPSC
12352200
Target
Calcium Channel
Type
Biochemical Assay Reagents
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/thio-nadp.html
Solubility
10 mM in DMSO
Smiles
O=P(O)(O)O[C@H]1[C@H](N2C3=NC=NC(N)=C3N=C2)O[C@@H]([C@H]1O)COP(OP(OC[C@H]4O[C@@H]([N+]5=CC=CC(C(N)=S)=C5)[C@@H]([C@@H]4O)O)([O-])=O)(O)=O
Molecular Formula
C21H28N7O16P3S
Molecular Weight
759.47
References & Citations
[1]Bizouarn T, et al. The involvement of NADP (H) binding and release in energy transduction by proton-translocating nicotinamide nucleotide transhydrogenase from Escherichia coli. Biochim Biophys Acta. 1995 Apr 4;1229 (1) :49-58.|[2]Dickey D M, et al. Thio-NADP is not an antagonist of NAADP[J]. Cell biochemistry and biophysics, 1998, 28: 63-73.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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