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Thio-NADP

Thio-NADP (S-NADP) is a nicotinic acid adenine dinucleotide phosphate (NAADP) inhibitor. Thio-NADP activates partial Ca2+ release[1].

Product Specifications

CAS Number

19254-05-8

Product Name Alternative

S-NADP

UNSPSC

12352200

Target

Calcium Channel

Type

Biochemical Assay Reagents

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/thio-nadp.html

Solubility

10 mM in DMSO

Smiles

O=P(O)(O)O[C@H]1[C@H](N2C3=NC=NC(N)=C3N=C2)O[C@@H]([C@H]1O)COP(OP(OC[C@H]4O[C@@H]([N+]5=CC=CC(C(N)=S)=C5)[C@@H]([C@@H]4O)O)([O-])=O)(O)=O

Molecular Formula

C21H28N7O16P3S

Molecular Weight

759.47

References & Citations

[1]Bizouarn T, et al. The involvement of NADP (H) binding and release in energy transduction by proton-translocating nicotinamide nucleotide transhydrogenase from Escherichia coli. Biochim Biophys Acta. 1995 Apr 4;1229 (1) :49-58.|[2]Dickey D M, et al. Thio-NADP is not an antagonist of NAADP[J]. Cell biochemistry and biophysics, 1998, 28: 63-73.

Shipping Conditions

Room temperature

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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