MMP-13-IN-1
MMP-13-IN-1 is a potent and selective inhibitor of MMP-13 with a IC50 value of 16 nM. MMP-13-in-1 can be used for atherosclerosis research[1].
Product Specifications
CAS Number
2925249-49-4
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mmp-13-in-1.html
Solubility
10 mM in DMSO
Smiles
FC(C(C)=C1)=CC=C1CNC(C2=NC3=C(C(N2)=O)C(OCCF)=C(C=C3)F)=O
Molecular Formula
C19H16F3N3O3
Molecular Weight
391.34
References & Citations
[1]Buchler A, et al. Quinazoline-2-Carboxamides as Selective PET Radiotracers for Matrix Metalloproteinase-13 Imaging in Atherosclerosis. J Med Chem. 2023 May 25;66 (10) :6682-6696.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-13
Frequently Asked Questions
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