Anticancer agent 118
Anticancer agent 118, a N‑acylated ciprofloxacin derivative, has anti-bacterial and anticancer activities. Anticancer agent 118 shows high activity against Gram-positive strains and antiproliferative activities against prostate PC3 cells. Anticancer agent 118 can be used for antitumor research[1].
Product Specifications
CAS Number
864443-43-6
UNSPSC
12352005
Target
Apoptosis; Bacterial; Necroptosis
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-118.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CCN(C(CCl)=O)CC4)=C3)C1=O)O
Molecular Formula
C19H19ClFN3O4
Molecular Weight
407.82
References & Citations
[1]Struga M, et.al. N-Acylated Ciprofloxacin Derivatives: Synthesis and In Vitro Biological Evaluation as Antibacterial and Anticancer Agents. ACS Omega. 2023 May 18;8 (21) :18663-18684.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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