1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine
1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine is a glycerophosphorylcholine, consisting of glycerol phosphate, choline and palmitic acid. It accumulates in vivo at sites of oxidative stress. 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine may be a ligand of scavenger receptors class B, while oxidized phospholipids oxPC (CD36) are potent ligands of scavenger receptors class B (CD36 and SR-BI) . Oxidized phospholipids (oxPLs) also play an important role in tumor apoptosis, may be elevated in malignant biliary strictures[1][2].
Product Specifications
CAS Number
89947-80-8
UNSPSC
12352211
Target
Scavenger Receptor Class B type I (SR-BI)
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-palmitoyl-2-succinyl-sn-glycerophosphorylcholine.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
C[N+](C)(C)CCOP(OC[C@H](OC(CCC(O)=O)=O)COC(CCCCCCCCCCCCCCC)=O)([O-])=O
Molecular Formula
C28H54NO10P
Molecular Weight
595.70
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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