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F-CRI1

F-CRI1 is a potent STING agonist with a Kd value of 40.62 nM. F-CRI1 is a radioactive probe with 18F-labeled modification. F-CRI1 can be used to study STING visualization in the tumor microenvironment[1].

Product Specifications

CAS Number

2991453-50-8

UNSPSC

12352005

Target

STING

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/f-cri1.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(N(C3=C1C=C(C=C3)OC)CC4=CN(N=N4)CCOCCF)C(C)=C(C)C=C2

Molecular Formula

C23H25FN4O3

Molecular Weight

424.47

References & Citations

[1]Liu H, et, al. Development of 18F-Labeled Acridone Analogue for Tumor Imaging via Stimulator of Interferon Genes Targeting. Mol Pharm. 2023 Jul 3;20 (7) :3529-3538.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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