F-CRI1
F-CRI1 is a potent STING agonist with a Kd value of 40.62 nM. F-CRI1 is a radioactive probe with 18F-labeled modification. F-CRI1 can be used to study STING visualization in the tumor microenvironment[1].
Product Specifications
CAS Number
2991453-50-8
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/f-cri1.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(N(C3=C1C=C(C=C3)OC)CC4=CN(N=N4)CCOCCF)C(C)=C(C)C=C2
Molecular Formula
C23H25FN4O3
Molecular Weight
424.47
References & Citations
[1]Liu H, et, al. Development of 18F-Labeled Acridone Analogue for Tumor Imaging via Stimulator of Interferon Genes Targeting. Mol Pharm. 2023 Jul 3;20 (7) :3529-3538.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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