1- (3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl) thymine
Selected Variant
HY-154686
Size: 1 Each
1- (3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl) thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
66503-47-7
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-3-β-azido-2-3-dideoxy-5-o-trityl-d-threopenta-furanosyl-thymine.html
Solubility
10 mM in DMSO
Smiles
CC1=CN(C(NC1=O)=O)[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)[C@H](N=[N+]=[N-])C2
Molecular Formula
C29H27N5O4
Molecular Weight
509.56
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Price
Frequently Asked Questions
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