9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine
Product Specifications
UNSPSC Description
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/9-3-deoxy-3-fluoro-β-d-ribofuranosyl-9h-purin-2-amine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](F)[C@@H](O)[C@H](N2C=NC3=C2N=C(N)N=C3)O1
Molecular Weight
269.23
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154643/9-3-Deoxy-3-fluoro-β-D-ribofuranosyl-9H-purin-2-amine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154643/
Clinical Information
No Development Reported
CAS Number
1612192-04-7
Curated Selection
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