N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine
Selected Variant
HY-154627
Size: 1 Each
N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
2382942-31-4
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n2-ibu-5-o-dmtr-2-o-hexadecanyl-guanosine.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](OCCCCCCCCCCCCCCCC)[C@H](N(C=N2)C3=C2C(NC(NC(C(C)C)=O)=N3)=O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
Molecular Formula
C51H69N5O8
Molecular Weight
880.12
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Price
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