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2’-O-Hexadecanyl-2-aminoadenosine

2’-O-Hexadecanyl-2-aminoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

2382942-28-9

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-o-hexadecanyl-2-aminoadenosine.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@@H](OCCCCCCCCCCCCCCCC)[C@H](N(C=N2)C3=C2C(N)=NC(N)=N3)O[C@@H]1CO

Molecular Formula

C26H46N6O4

Molecular Weight

506.68

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Frequently Asked Questions

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