N6-Bz-5’-O-DMTr-2’-O-hexadecanyl adenosine
N6-Bz-5’-O-DMTr-2’-O-hexadecanyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
2382942-34-7
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n6-bz-5-o-dmtr-2-o-hexadecanyl-adenosine.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@H]([C@H](N(C=N2)C3=C2C(NC(C4=CC=CC=C4)=O)=NC=N3)O[C@@H]1COC(C5=CC=CC=C5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)OCCCCCCCCCCCCCCCC
Molecular Formula
C54H67N5O7
Molecular Weight
898.14
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
TAG-72 / CA72.4 (B72.3), CF568 conjugate, 0.1mg/mL
MUC18 / Mucin 18 / CD146 (OJ79c), CF568 conjugate, 0.1mg/mL
TGF-beta (1D11.16.8), CF594 conjugate, 0.1mg/mL
