2’-Bromo-2’-deoxy-5-fluorouridine
Product Specifications
UNSPSC Description
2’-Bromo-2’-deoxy-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-bromo-2-deoxy-5-fluorouridine.html
Solubility
10 mM in DMSO
Smiles
O=C(C(F)=C1)NC(N1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2Br)=O
Molecular Weight
325.09
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154609/2-Bromo-2-deoxy-5-fluorouridine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154609/
Clinical Information
No Development Reported
CAS Number
32791-82-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1081030-01 0.05 mg (E-Coli)
Recombinant Hadronyche formidabilis Kappa-hexatoxin-Hf1a
Ask
View Details MBS1081030-02 0.2 mg (E-Coli)
Recombinant Hadronyche formidabilis Kappa-hexatoxin-Hf1a
Ask
View Details