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3',5'-Di-O-benzoyl fialuridine

Selected Variant

HY-154589

Size: 1 Each

3',5'-Di-O-benzoyl fialuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

97614-45-4

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3-5-di-o-benzoyl-fialuridine.html

Solubility

10 mM in DMSO

Smiles

O=C(C(I)=CN1[C@H]2[C@@H](F)[C@H](OC(C3=CC=CC=C3)=O)[C@@H](COC(C4=CC=CC=C4)=O)O2)NC1=O

Molecular Formula

C23H18FIN2O7

Molecular Weight

580.30

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Price

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