2’-Deoxy-O6-[2- (4-nitrophenylethyl) ]guanosine
2’-Deoxy-O6-[2- (4-nitrophenylethyl) ]guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
86137-72-6
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-deoxy-o6-2-4-nitrophenylethyl-guanosine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O)C[C@H](N2C=NC3=C2N=C(N)N=C3OCCC4=CC=C([N+]([O-])=O)C=C4)O1
Molecular Formula
C18H20N6O6
Molecular Weight
416.39
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
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