5’-Deoxy-5’-N-(2-chloroethyl)amino thymidine
Product Specifications
UNSPSC Description
5’-Deoxy-5’-N-(2-chloroethyl)amino thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-deoxy-5-n-2-chloroethyl-amino-thymidine.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(C(C)=C1)=O)N1[C@@H]2O[C@H](CNCCCl)[C@@H](O)C2
Molecular Weight
303.74
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154567/5-Deoxy-5-N-2-chloroethyl-amino-thymidine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154567/
Clinical Information
No Development Reported
CAS Number
2305415-99-8
Curated Selection
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