3’-O-MOE-5Me-C (Bz) -2’-phosphoramidite
3’-O-MOE-5Me-C (Bz) -2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[1098233-10-3]
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-o-moe-5me-c-bz-2-phosphoramidite.html
Solubility
10 mM in DMSO
Smiles
COC(C=C1)=CC=C1C(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)OC[C@H]4O[C@@H](N5C(NC(NC(C6=CC=CC=C6)=O)C(C)=C5)=O)[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H]4OCCOC
Molecular Formula
C50H62N5O10P
Molecular Weight
924.03
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Explore Other Products
Browse additional items from our catalog
ELISA kit for Canine Superoxide dismutase (SOD)
ELISA kit for Canine Superoxide dismutase (SOD)
ELISA kit for Canine Superoxide dismutase (SOD)
Lentiviral human WDR91 sgRNA gene knockout kit - Lentiviral human WDR91 sgRNA gene knockout kit (100)
