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3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite

Product Specifications

UNSPSC Description

3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Target Antigen

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3-o-moe-5me-c-bz-2-phosphoramidite.html

Solubility

10 mM in DMSO

Smiles

COC(C=C1)=CC=C1C(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)OC[C@H]4O[C@@H](N5C(NC(NC(C6=CC=CC=C6)=O)C(C)=C5)=O)[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H]4OCCOC

Molecular Weight

924.03

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-154546/3-O-MOE-5Me-C-Bz-2-phosphoramidite-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-154546/

Clinical Information

No Development Reported

CAS Number

1098233-10-3

Curated Selection

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