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5’-O-DMTr-3’-O-phthalimidopropyl cytidine

5’-O-DMTr-3’-O-phthalimidopropyl cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-o-dmtr-3-o-phthalimidopropyl-cytidine.html

Solubility

10 mM in DMSO

Smiles

O[C@@H]1[C@H](OCCCN2C(C3=CC=CC=C3C2=O)=O)[C@@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)O[C@H]1N7C=CC(N)=NC7=O

Molecular Formula

C41H40N4O9

Molecular Weight

732.78

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Frequently Asked Questions

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