5-Bromo-2’-deoxy-2’-fluoro-β-D-arabinouridine
5-Bromo-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
69123-97-3
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-bromo-2-deoxy-2-fluoro-β-d-arabinouridine.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@H](F)[C@@H](O[C@@H]1CO)N(C(N2)=O)C=C(Br)C2=O
Molecular Formula
C9H10BrFN2O5
Molecular Weight
325.09
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
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