3’-O-Me-G (iBu) -2’-phosphoramidite
3’-O-Me-G (iBu) -2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) [1].
Product Specifications
CAS Number
179479-04-0
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-o-me-g-ibu-2-phosphoramidite.html
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N([C@H]3[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@H](OC)[C@@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)O3)C=N2)NC(NC(C(C)C)=O)=N1
Molecular Formula
C45H56N7O9P
Molecular Weight
869.94
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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