2-Amino-6-chloro-9- (3-deoxy-beta-D-ribofuanosyl) -9H-purine
Selected Variant
HY-154477
Size: 1 Each
2-Amino-6-chloro-9- (3-deoxy-beta-D-ribofuanosyl) -9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
1055035-48-7
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-amino-6-chloro-9-3-deoxy-beta-d-ribofuanosyl-9h-purine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1C[C@@H](O)[C@H](N2C=NC3=C2N=C(N)N=C3Cl)O1
Molecular Formula
C10H12ClN5O3
Molecular Weight
285.69
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Price
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