2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine
Product Specifications
UNSPSC Description
2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-amino-6-chloro-9-3-deoxy-beta-d-ribofuanosyl-9h-purine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1C[C@@H](O)[C@H](N2C=NC3=C2N=C(N)N=C3Cl)O1
Molecular Weight
285.69
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154477/2-Amino-6-chloro-9-3-deoxy-beta-D-ribofuanosyl-9H-purine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154477/
Clinical Information
No Development Reported
CAS Number
1055035-48-7
Curated Selection
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