3’-Deoxy-2’,5’-di-O-acetyl-8-hydroxyguanosine
Product Specifications
UNSPSC Description
3’-Deoxy-2’,5’-di-O-acetyl-8-hydroxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-deoxy-2-5-di-o-acetyl-8-hydroxyguanosine.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(N)=NC2=C1N=C(O)N2[C@@H]3O[C@H](COC(C)=O)C[C@H]3OC(C)=O
Molecular Weight
367.31
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154454/3-Deoxy-2-5-di-O-acetyl-8-hydroxyguanosine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154454/
Clinical Information
No Development Reported
CAS Number
2389988-72-9
Curated Selection
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