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2'-Deoxy-N2-isopropyl guanosine

Product Specifications

UNSPSC Description

2’-Deoxy-N2-isopropyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Target Antigen

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-deoxy-n2-isopropyl-guanosine.html

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1[C@@H](O)C[C@H](N2C(N=C(NC(C)C)NC3=O)=C3N=C2)O1

Molecular Weight

309.32

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-154428/2-Deoxy-N2-isopropyl-guanosine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-154428/

Clinical Information

No Development Reported

CAS Number

201528-73-6

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