8-Chloro-2’-deoxy-2’-fluoroadenosine
8-Chloro-2’-deoxy-2’-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-chloro-2-deoxy-2-fluoroadenosine.html
Solubility
10 mM in DMSO
Smiles
F[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N(C(Cl)=N2)C3=C2C(N)=NC=N3
Molecular Formula
C10H11ClFN5O3
Molecular Weight
303.68
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
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