2-Chloro-N6-cyclopentyl 2’-deoxy- adenosine

2-Chloro-N6-cyclopentyl 2’-deoxy- adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

[215108-39-7]

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-chloro-n6-cyclopentyl-2-deoxy-adenosine.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1C[C@H](N2C(N=C(Cl)N=C3NC4CCCC4)=C3N=C2)O[C@@H]1CO

Molecular Formula

C15H20ClN5O3

Molecular Weight

353.80

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Curated Selection

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