4’,5’-Didehydro-5’-deoxy thymidine
Product Specifications
UNSPSC Description
4’,5’-Didehydro-5’-deoxy thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-5-didehydro-5-deoxy-thymidine.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C)=C1)NC(N1[C@@H](C[C@@H]2O)OC2=C)=O
Molecular Weight
224.21
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154348/4-5-Didehydro-5-deoxy-thymidine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154348/
Clinical Information
No Development Reported
CAS Number
28034-72-2
Curated Selection
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