3′-Azido-3′-deoxy-5′-O- (triphenylmethyl) thymidine
3′-Azido-3′-deoxy-5′-O- (triphenylmethyl) thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[29706-84-1]
UNSPSC
12352005
Hazard Statement
H312-H400-H410
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-azido-3-deoxy-5-o-triphenylmethyl-thymidine.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C)=C1)NC(N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)[C@@H](N=[N+]=[N-])C2)=O
Molecular Formula
C29H27N5O4
Molecular Weight
509.56
Precautions
P273-P280-P302+P352-P362+P364-P391-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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