2’,3’-Isopropylidene-5-hydroxyuridine
2’,3’-Isopropylidene-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[20406-82-0]
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-3-isopropylidene-5-hydroxyuridine.html
Solubility
10 mM in DMSO
Smiles
O=C(C(O)=CN1[C@H]2[C@H](OC(C)(C)O3)[C@H]3[C@@H](CO)O2)NC1=O
Molecular Formula
C12H16N2O7
Molecular Weight
300.26
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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