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5’-O-DMTr-N6-ethyl-2’-deoxyadenosine 3’-CED phosphoramidite

Product Specifications

UNSPSC Description

5’-O-DMTr-N6-ethyl-2’-deoxyadenosine 3’-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Target Antigen

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-o-dmtr-n6-ethyl-2-deoxyadenosine-3-ced-phosphoramidite.html

Solubility

10 mM in DMSO

Smiles

CCNC1=NC=NC2=C1N=CN2[C@H](O[C@@H]3COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C[C@@H]3OP(N(C(C)C)C(C)C)OCCC#N

Molecular Weight

781.88

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-154264/5-O-DMTr-N6-ethyl-2-deoxyadenosine-3-CED-phosphoramidite-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-154264/

Clinical Information

No Development Reported

Curated Selection

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