5’-O-DMTr-N6-ethyl-2’-deoxyadenosine 3’-CED phosphoramidite
5’-O-DMTr-N6-ethyl-2’-deoxyadenosine 3’-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-o-dmtr-n6-ethyl-2-deoxyadenosine-3-ced-phosphoramidite.html
Solubility
10 mM in DMSO
Smiles
CCNC1=NC=NC2=C1N=CN2[C@H](O[C@@H]3COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C[C@@H]3OP(N(C(C)C)C(C)C)OCCC#N
Molecular Formula
C42H52N7O6P
Molecular Weight
781.88
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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