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Rev 2’-O-MOE-G (iBu) -5’-amidite

Rev 2’-O-MOE-G (iBu) -5’-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

725223-44-9

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rev-2-o-moe-g-ibu-5-amidite.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(N([C@H]3[C@H](OCCOC)[C@H](OC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](COP(N(C(C)C)C(C)C)OCCC#N)O3)C=N2)N=C(NC(C(C)C)=O)N1

Molecular Formula

C47H60N7O10P

Molecular Weight

913.99

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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