5- (3-Azidopropyl) uridine
5- (3-Azidopropyl) uridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. 5- (3-Azidopropyl) uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
1354419-08-1
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-3-azidopropyl-uridine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@H](O)[C@H](O)[C@H](N2C=C(CCCN=[N+]=[N-])C(NC2=O)=O)O1
Molecular Formula
C12H17N5O6
Molecular Weight
327.29
References & Citations
[1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16 (9) :7980-93.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
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