2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone
2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-o-benzoyl-3-o-t-butyldiphenylsilyl-l-threono-lactone.html
Solubility
10 mM in DMSO
Smiles
O=C1OC[C@H](O[Si](C2=CC=CC=C2)(C(C)(C)C)C3=CC=CC=C3)[C@H]1OC(C4=CC=CC=C4)=O
Molecular Formula
C27H28O5Si
Molecular Weight
460.59
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154218/2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono-lactone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154218/
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
CAS Number
[1446785-28-9]
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