2',3',5'-Tri-O-benzoyl-6-azauridine
Product Specifications
UNSPSC Description
2',3',5'-Tri-O-benzoyl-6-azauridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-3-5-tri-o-benzoyl-6-azauridine.html
Solubility
10 mM in DMSO
Smiles
O=C(C=N1)NC(N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)=O)[C@@H](OC(C4=CC=CC=C4)=O)[C@H]2OC(C5=CC=CC=C5)=O)=O
Molecular Weight
557.51
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154190/2-3-5-Tri-O-benzoyl-6-azauridine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154190/
Clinical Information
No Development Reported
CAS Number
1627-29-8
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