5- (2-Hydroxyethyl) -2’-deoxy uridine

5- (2-Hydroxyethyl) -2’-deoxy uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

[90301-60-3]

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-2-hydroxyethyl-2-deoxy-uridine.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1C[C@H](N2C=C(CCO)C(NC2=O)=O)O[C@@H]1CO

Molecular Formula

C11H16N2O6

Molecular Weight

272.25

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Curated Selection

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