2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium
2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-deoxy-2-fluoroguanosine-5-monophosphate-triethyl-ammonium.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](F)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1COP(O)(O)=O.CCN(CC)CC.CCN(CC)CC
Molecular Formula
C22H43FN7O7P
Molecular Weight
567.59
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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