N- (1-Oxopropyl) cytidine

N- (1-Oxopropyl) cytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

Product Specifications

CAS Number

[60107-04-2]

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-1-oxopropyl-cytidine.html

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(NC(CC)=O)C=C2)=O)O1

Molecular Formula

C12H17N3O6

Molecular Weight

299.28

References & Citations

[1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3 (11) :1062-8.