5-Nitro-1- (3-azido-3-deoxy-β-D-ribofuranosyl) -2 (1H) -pyridinone

5-Nitro-1- (3-azido-3-deoxy-β-D-ribofuranosyl) -2 (1H) -pyridinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 5-Nitro-1- (3-azido-3-deoxy-β-D-ribofuranosyl) -2 (1H) -pyridinone is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.