6-Aza-2'-deoxyuridine

6-Aza-2'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

[20500-29-2]

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/6-aza-2-deoxyuridine.html

Solubility

10 mM in DMSO

Smiles

O=C(C=N1)NC(N1[C@@H]2O[C@H](CO)[C@@H](O)C2)=O

Molecular Formula

C8H11N3O5

Molecular Weight

229.19

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Curated Selection

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