3-Deoxy-1,2:5,6-bis-O- (1-methylethylidene) -α-D-ribo-hexofuranose
3-Deoxy-1,2:5,6-bis-O- (1-methylethylidene) -α-D-ribo-hexofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[4613-62-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-deoxy-1-2-5-6-bis-o-1-methylethylidene-α-d-ribo-hexofuranose.html
Solubility
10 mM in DMSO
Smiles
CC1(C)O[C@H]2O[C@H]([C@@]3([H])COC(C)(C)O3)C[C@H]2O1
Molecular Formula
C12H20O5
Molecular Weight
244.28
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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