2’-O-Acetyl-5’-O- (p-toluoyl) -3’-deoxy-3’-fluoro-5-fluorouridine
Selected Variant
HY-154078
Size: 1 Each
2’-O-Acetyl-5’-O- (p-toluoyl) -3’-deoxy-3’-fluoro-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
2072145-63-0
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-o-acetyl-5-o-p-toluoyl-3-deoxy-3-fluoro-5-fluorouridine.html
Solubility
10 mM in DMSO
Smiles
F[C@H]1[C@@H](OC(C)=O)[C@H](N2C(NC(C(F)=C2)=O)=O)O[C@@H]1COC(C3=CC=C(C)C=C3)=O
Molecular Formula
C19H18F2N2O7
Molecular Weight
424.35
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Price
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