2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-fluorouridine
Product Specifications
UNSPSC Description
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-o-acetyl-5-o-p-toluoyl-3-deoxy-3-fluoro-5-fluorouridine.html
Solubility
10 mM in DMSO
Smiles
F[C@H]1[C@@H](OC(C)=O)[C@H](N2C(NC(C(F)=C2)=O)=O)O[C@@H]1COC(C3=CC=C(C)C=C3)=O
Molecular Weight
424.35
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-154078/2-O-Acetyl-5-O-p-toluoyl-3-deoxy-3-fluoro-5-fluorouridine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-154078/
Clinical Information
No Development Reported
CAS Number
2072145-63-0
Curated Selection
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