2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium

2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-deoxy-2-fluorouridine-5-monophosphate-triethyl-ammonium.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@@H](F)[C@H](N2C(NC(C=C2)=O)=O)[o][C@@H]1COP(O)(O)=O.CCN(CC)CC.CCN(CC)CC

Molecular Formula

C21H42FN4O7P

Molecular Weight

512.55

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Curated Selection

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