N4-Acetyl-5’-O- (4,4’-dimethoxytrityl) -2’-deoxycytidine
N4-Acetyl-5’-O- (4,4’-dimethoxytrityl) -2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[121058-82-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n4-acetyl-5-o-4-4-dimethoxytrityl-2-deoxycytidine.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O[C@H]1C[C@H](N2C=CC(NC(C)=O)=NC2=O)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5
Molecular Formula
C32H33N3O7
Molecular Weight
571.62
Precautions
H302, H315, H319
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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